Professor Pandit, working among the admirable group of philosophers at the University of Delhi, has written a fundamental criticism and a constructive re-interpretation of all that has been preserved as serious epistemological and methodological reflections on the sciences in modern Western philosoph- from the times of Galileo, Newton, Descartes and Leibniz to those of Russell and Wittgenstein, Carnap and Popper, and, we need hardly add, onward to the troubling relativisms and reconstructions of historical epistemologies in the works of Hanson, Kuhn, (...) Lakatos and Feyerabend. His themes are intrigu ing, set forth as they are with masterly case studies of physics and the life sciences, and within an original conceptual framework for philosophical analysis of the processes, functions, and structures of scientific knowing. Pandit's contributions deserve thoughtful examination. For our part, we wish to point to some among them: (1) an interactive articulation of subjective and objective factors of both problems and theories in the course of scientific development; (2) a striking contrast between the explanatory power of a scientific theory and its 'resolving power', i. e. (shrink)

Canada has a marked shortfall between the supply and demand for kidneys for transplantation. Median wait times for deceased donor kidney transplantation vary from 5.8 years in British Columbia, 5.2 years in Manitoba and 4.5 years in Ontario to a little over 2 years in Quebec and Nova Scotia. Living donation provides a viable option for some, but not all people. Consequently, a small number of people travel abroad to undergo kidney transplantation by commercial means. The extent to which they (...) are aware of the potential risks to their health and the health of the kidney vendors is unclear. Travel abroad to obtain a kidney commercially i.e. transplant tourism (TT), raises ethical issues which include the exploitation of the poor, uncertainty of donor informed consent to nephrectomy, poor clinical care and lack of follow up for the donor, commodification of the body and inequity of access to medical care for donors. Also, TT widens socioeconomic disparities in access to transplantation, differing from the Canadian system of universal coverage for healthcare. The Canadian transplant community has discussed how to respond to patients who plan to travel abroad for TT or return with a purchased kidney. Unease rests in the tension between the duty to care for legitimate Canadian residents and the unwillingness to enable TT. This paper discusses three anonymized cases and the Canadian responses to TT as recorded in academic literature and a formal statement by relevant professional bodies. (shrink)

Proximity and interpersonal contact are prominent components of social connection. Giving affective touch to others is fundamental for human bonding. This brief report presents preliminary results from a pilot study. It explores if exposure to bonding scenes impacts the activity of specific muscles related to physical interaction. Fingers flexion is a very important component when performing most actions of affectionate contact. We explored the visuo-motor affective interplay by priming participants with bonding scenes and assessing the electromyographic activity of the fingers (...) flexor muscle, in the absence of any overt movements. Photographs of dyads in social interaction and of the same dyads not interacting were employed. We examined the effects upon the electromyographical activity: during the passive exposure to pictures, and during picture offset and when expecting the signal to perform a fingers flexion task. Interacting dyads compared to matched non-interacting dyads increased electromyographic activity of the fingers flexor muscle in both contexts. Specific capture of visual bonding cues at the level of visual cortex had been described in the literature. Here we showed that the neural processing of visual bonding cues reaches the fingers flexor muscle. Besides, previous visualization of bonding cues enhanced background electromyographic activity during motor preparation to perform the fingers flexion task, which might reflect a sustained leakage of central motor activity downstream leading to increase in firing of the respective motor neurons. These data suggest, at the effector level, an implicit visuo-motor connection in which social interaction cues evoke intrinsic dispositions toward affectionate social behavior. (shrink)

Background: More and more quantitative information is becoming available about the risks of complications arising from medical treatment. In everyday practice, this raises the question whether each and every risk, however low, should be disclosed to patients. What could be good reasons for doing or not doing so? This will increasingly become a dilemma for practitioners.Objective: To report doctors’ views on whether to disclose or withhold information on low risks of complications.Methods: In a qualitative study design, 37 respondents were included. (...) Focus group interviews were held with 22 respondents and individual in-depth interviews with 15.Results: Doctors have doubts about disclosing or withholding information on complication risk, especially in a risk range of 1 in 200 to 1 in 10 000. Their considerations on whether to disclose or to withhold information depend on a complicated mix of patient and doctor-associated reasons; on medical and personal considerations; and on the kind and purpose of intervention.Discussion: Even though the degree of a risk is important in a doctor’s considerations, the severity of the possible complications and patients’ wishes and competencies have an important role as well. Respondents said that low risks should always be communicated when there are alternatives for the intervention or when the patient may prevent or mitigate the risk. When the appropriateness of disclosing risks is doubtful, doctors should always tell their patients that no intervention is without risk, give them the opportunity to gather all the information they need or want, and enable them to detect a complication at an early stage. (shrink)

Background Residual dried blood spots (rDBS) from newborn screening programmes represent a valuable resource for medical research, from basic sciences, through clinical to public health. In Hong Kong, there is no legislation for biobanking. Parents’ view on the retention and use of residual newborn blood samples could be cultural-specific and is important to consider for biobanking of rDBS. Objective To study the views and concerns on long-term storage and secondary use of rDBS from newborn screening programmes among Hong Kong Chinese (...) parents. Methods A mixed-method approach was used to study the views and concerns on long-term storage and secondary use of rDBS from newborn screening programmes among Hong Kong Chinese parents of children 0–3 years or expecting parents through focus groups (8 groups; 33 participants) and a survey (n = 1012, 85% mothers) designed with insights obtained from the focus groups. We used framework analysis to summarise the themes as supportive factors, concerns and critical arguments for retention and secondary use of rDBS from focus group discussion. We used multiple logistic regression to assess factors associated with support for retention and secondary use of rDBS in the survey. Results Both in focus groups and survey, majority of parents were not aware of the potential secondary use of rDBS. Overall secondary use of rDBS in medical research was well accepted by a large proportion of Hong Kong parents, even if all potential future research could not be specified in a broad consent. However parents were concerned about potential risks of biobanking rDBS including leaking of data and mis-use of genetic information. Parents wanted to be asked for permission before rDBS are stored and mainly did not accept an “opt-out” approach. The survey showed that parents born in mainland China, compared to Hong Kong born parents, had lower awareness of newborn screening but higher support in biobanking rDBS. Higher education was associated with support in rDBS biobanking only among fathers. Conclusion Long-term storage and secondary use of rDBS from newborn screening for biomedical research and a broad consent for biobanking of rDBS are generally acceptable to Hong Kong parents given their autonomy is respected and their privacy is protected, highlighting the importance of an accountable governance and a transparent access policy for rDBS biobanks. (shrink)

This book explores the universe and its subsystems from the three lenses of evolutionary (diversifying), developmental (converging), and complex (adaptive) processes at all scales. It draws from prolific experts within the academic disciplines of complexity science, physical science, information and computer science, theoretical and evo-devo biology, cosmology, astrobiology, evolutionary theory, developmental theory, and philosophy. The chapters come from a Satellite Meeting, "Evolution, Development and Complexity" (EDC) hosted at the Conference on Complex Systems, in Cancun, 2017. The contributions will be peer-reviewed (...) and contributors from outside the conference will be invited to submit chapters to ensure full coverage of the topics. This book explores many issues within the field of EDC such as the interaction of evolutionary stochasticity and developmental determinism in biological systems and what they might teach us about these twin processes in other complex systems. This text will appeal to students and researchers within the complex systems and EDC fields.. (shrink)

Обобщен опыт работы по диагностике микробиологических повреждений памятников искусства и культуры. Большой иллюстративный материал и конкретные примеры проведения микологических экспертиз памятников помогут разобраться в представленном материале.

The reader of Demosthenes can hardly avoid the impression that there was something sadly awry with the Athenian naval system in the two decades prior to Chaeronea. The war in the north Aegean was essentially a naval war, and Demosthenes frequently enough blamedAthen's failure on her lack of preparation. ‘Why do you think, Athenians,… that all our expeditionary forces are too late for the critical moments?…In the business of the war and the preparation for it everything is in disorder, unreformed, (...) undefined. So it is that some news arrives, we appoint trierarchs, we give them the opportunity legally to get others to act in their stead, we consider provision of money, then it is decided that the metics and those “living out” should go on the ships, then again you yourselves, then to allow substitutes, and during these delays^the cause for which we would have been sailing is lost before we have sailed] For we spend the time for action on preparations, but the critical moments for action do not last as long as our dilatoriness and cautious procedures’ . This was spoken in 351 and it is much the same a decade later. (shrink)

Anselm: I agreed that Pegasus is a flying horse according to the stories people tell, the paintings painters paint and so on . That is, Pegasus is a flying horse in the understanding of storytellers, their readers and the artists who depict Pegasus. You asked whether flying is not an unmediated causal power . Well, it could be an unmediated causal power if you or I had it, but not if a being with only mediated powers had it. And so (...) poor Pegasus, a being whose powers are only those given him by storytellers and artists, has only the mediated power of flying that they have given him. He flies in the thoughts and depictions of beings with unmediated powers. Still, Pegasus has not only the mediated power to fly but also the mediated power to entertain us, and perhaps even inspire us. Fool: But people could tell stories about you, too, about how you sprouted wings and flew onto the roof of Canterbury Cathedral. Anselm: Alas, if it were only in stories that I could do that, then flying would not be an unmediated causal power of mine. I would still have unmediated causal powers all right, and so would be greater than Pegasus. But flying is not one of my unmediated causal powers. However, something than which nothing greater can be conceived would, and does, as I have proved in my Proslogion, have unmediated causal powers – indeed, much greater unmediated causal powers than any poor mortals like you and me.1 •↵1 For …. (shrink)

The ethical pre-condition of randomised controlled trials is, at present, the presence of equipoise. This refers to an opinion of the investigator that there is uncertainty as to the merits of the treatments being compared. It is argued that since the decision to enrol is the potential subject’s, the investigator’s opinion is not ethically relevant. It is proposed instead that equipoise be patient-centred, and that a trial is in equipoise for a patient when enrolling gives them the same chance of (...) a good outcome as not enrolling. It is shown that trial enrolment is normally easily the best strategy for achieving a good outcome, and that trials currently thought to be unethical may be in patient-centred equipoise. This is so for three reasons: (1) patients in trials receive superior care, (2) trial enrolment minimises the risk of being a victim of a therapeutic disaster and (3) health professionals make mistakes, and a 50% chance of receiving the worse treatment until a trial reports is always better than any chance of receiving the worse treatment indefinitely. It is concluded that so long as the standard of professional conduct is the furtherance of patients’ objective interests randomised controlled trials are ethical. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Philosophy and Rhetoric 36.3 (2003) 207-222 [Access article in PDF] Burke Contra Kierkegaard:Kenneth Burke's Dialectic via Reading Søren Kierkegaard G. L. Ercolini Isaac—to his children Lived to tell the tale— Moral—with a Mastiff Manners may prevail. —Emily Dickinson Kenneth Burke employs the term dialectic throughout his works and yet, despite its profuse recurrence, the term remains ambiguous. Much secondary scholarship has focused on Burke and dialectics, and still the (...) term in Burke remains—if not already complicated—cloudy. 1 Part of the difficulty regarding this term stems from Burke's own ambiguity; another part from critics' tendency to rely on Burke's own use and definitions for clarification of this concept. The arguments have been helpful and illuminating, yet Burke's dialectic can be further clarified by going beyond what Burke means by the term by focusing on how he deploys dialectical criticism in his own work. 2 This article focuses on Burke's appropriation of the existential thinker Søren Kierkegaard as a particularly clear and remarkable instance of the operation of Burke's dialectic in his criticism. I maintain that although Burke's reading of Kierkegaard is arguably a misreading, his strategic appropriation of Kierkegaard in A Rhetoric of Motives (1950) not only serves as a clear deployment of the dialectic, but also functions as a foil against which Burke defines his own critical method. Burke's reading of Kierkegaard emphasizes the function of resolution in Burke's critical project.The current literature, although quite informative, does not put Burke's dialectic in sharp focus. Rueckert argues that Burkean dialectics "is really a branch of what Burke was to later call logology, the study of words, of language, of symbol systems" (1994, 14). Heath claims that dialectic "is an analytical tool to help us diagnose perspectives so that we can [End Page 207] examine whether they make sense and consider their implications for social relations" (1986, 162). Crusius contends that, "dialectic for Burke is the study of verbal universes, the disinterested pursuit of a vocabulary's implications" (1986, 24). While Brummett and Crusius show similarity between Hegel's and Burke's dialectic, Heath and Wess distinguish Burke's dialectic from Hegelian idealism and teleological history respectively. 3 Most of the arguments concerning Burke and dialectic focus on "The Dialectic of Constitutions" in A Grammar of Motives (1969), while A Rhetoric of Motives (1962), where Burke identifies humankind as homo dialecticus, is hardly engaged with regard to this concept. 4 Burke's working through Kierkegaard in A Rhetoric of Motives demonstrates Burke's dialectical criticism—thus providing an operational account of Burke's dialectic—and allows for his revelation of the three motives in the realm of rhetoric: the Order, the Secret, and the Kill. 5 And yet, despite this centrality of Fear and Trembling, surprisingly little has been said about Burke's Kierkegaard beyond passing mention. 6Despite editorial advice to the opposite regarding an article that would later become a part of the book, Burke evidently regarded his reading of Kierkegaard as important. Joseph Bennett, editor of Hudson Review, responded as follows to Burke's 1948 submission of the article entitled "Imagery of Killing": "I would like to request that you eliminate Kierkegaard from the article in question, confining it simply to literary exegesis and excluding the philosopher theologian." 7 Although he complied for the article, Burke retained his reading of Kierkegaard in A Rhetoric of Motives. Despite the lack of attention given to it, Burke's engagement with Kierkegaard clearly demonstrates how Burke views ethical criticism as that which resolves opposition, negation, and paradox to a higher order. Burke contra Kierkegaard The section entitled "Order" in A Rhetoric of Motives contains a detailed, twenty-three-page discussion of Kierkegaard's Fear and Trembling. In this discussion, Burke primarily attacks Kierkegaard for encouraging what Burke enigmatically and elliptically identifies as the "cult of the Kill."Burke's portrayal of Kierkegaard is hardly flattering: at the crescendo of his analysis in A Rhetoric of Motives he claims that thinking such as Kierkegaard... (shrink)

v. 1. De l'ineffable et de l'Un -- v. 2. De la triade et de l'unifié -- v. 3. De la procession.

Enseignement de la morale et philosophie, qui inaugure la serie, s'inscrit dans le cadre d'un effort de valorisation de l'enseignement de la morale et de reflexion sur la place fondamentale de la philosophie dans la formation morale.